A 46-year-old woman with negative annual screening mammograms presented to her primary care physician with sense of fullness in the upper outer quadrant of right breast. Although the patient thought she could palpate a specific abnormality, physical examination did not reveal a well-defined mass. A diagnostic mammogram of the right breast showed a group of stable calcifications seen before and what appeared to be a new ill-defined area of minimally increased density and architectural distortion in the upper outer quadrant. A stereotactic core biopsy was followed by a sentinel lymph node biopsy and needle localization lumpectomy.
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